Hypersensitivity to the active substance(s) or to any of the excipients listed in Description; Inborn errors of amino acid metabolism; Hyperglycaemia not responding to insulin doses of up to 6 units insulin/hour; Intracranial or intraspinal haemorrhage; Acidosis; Severe hepatic insufficiency; Severe renal insufficiency in absence of renal replacement therapy.
On account of its composition, Nutriflex Peri/Nutriflex Plus must not be used in newborn infants, infants and toddlers < 2 years of age.
General contraindications to parenteral nutrition include: Unstable circulatory status with vital threat (e.g. states of collapse, shock, fluid overload, pulmonary oedema etc.); Acute myocardial infarction and stroke; Unstable metabolic condition (e.g. coma of unknown origin, hypoxia, decompensated diabetes mellitus etc).